A team of scientists from Duke University claim to have found a possible cure for treating one of the deadliest types of cancer, cancer of the brain. According to the researchers, the cure for brain cancer might be poliovirus.
The scientists working at Duke University’s Preston Robert Tisch Brain Tumor Center, conducted a study on a small number of patients diagnosed with brain cancer. The patients were followed for 10 months by CBS’s “60 Minutes”.
Dr. Matthias Gromeier, an expert in molecular biology at Duke University and one of the scientists involved in the study, has been researching this possible brain cancer cure for more than 15 years. He first began with studies, then moved on animal trials and currently he is investigating the effects on human trials.
For the study, the researchers injected into the patients’ brain tumor a genetically modified poliovirus.
During the study, 11 of the 22 volunteers did not survive the tumors. However, the researchers found that in two patients who had glioblastoma brain tumors, there were no signs of the cancer three years after the patients were injected with the genetically-modified poliovirus.
One of the participants in the experimental treatment is Stephanie Lipscomb. She was 20 when the experiment started.
In 2012, the scientists injected the modified polio into her brain tumor and three years later, she showed no signs of active cancer in her brain.
The doctors administered Lipscomb with only one dose of the modified polio. Lipscomb said that she was not expecting to live for more than 2 years because of her brain tumor.
Dr. Gromier explained that the genetically modified polio virus can fight the shield cancers put up against the human immune system. This helps the immune system fight back.
Dr. Gromier and his team modified the polio virus by adding certain genetic information collected from the rhinovirus, which is the virus responsible for the common cold.
According to the researchers, the polio virus once introduced in the human body starts to attack the cancer tumor and helps the immune system fight against the disease.
The researchers say that although the treatment proved to be successful, further studies are needed.
Image Source: abcnews
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