Breast cancer is growing as one of the biggest threat for women health. A new study has brought some shocking facts about the fatal disease into light.
According to the researchers who conducted the study, women with genes having mutations called PALB2 are at risk of developing breast cancer by the time they are 70. These mutations enable one in three chance of getting the disease.
The study also indicated that the new mutation PALB2 is as crucial risk factor as BRCA1 and BRCA2 mutations, the two widely known breast cancer risk genes.
The study was published on Wednesday in the New England Journal of Medicine.
For the study, the researchers analysed data from 154 families with no record of BRCA1 or BRCA2 mutations. The total families in the study had 362 members who had PALB2 gene mutations.
The researchers found that women with rare PALB2 gene mutations were on an average 35 percent at risk of developing breast cancer when they grew 70-year-old.
The researchers, however, noted that those who had family history of breast cancer were at high risk of developing the disease.
Peter Johnson, chief clinician at the charity Cancer Research UK, said, “We’re learning all the time about the different factors that may influence a woman’s chances of developing breast cancer.”
The charity Cancer Research UK partly funded the study.
Johnson further said, “This particular mutation doesn’t make people certain to develop cancer, but it’s another piece of information to help women make proper informed choices about how they may help to minimize their own risk.”
Breast cancer is emerging as the most common type of cancer in women across the world. The unhealthy lifestyle and lack of awareness is contributing to its rise. According to the World Health Organisation (WHO) reports, more than 508,000 women died due to breast cancer in 2011.
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