According to a study published in the journal Cell scientists have developed a new treatment for baldness which does not involve any expensive procedure. You can get rid of baldness by simply plucking out your hairs. It may sound weird, but this is precisely what will help your hair regenerate.
The lead author of the study was Chih-Chiang Chen, a dermatologist from Veterans General Hospital and National Yang-Ming University (Taiwan). He started working on this study about a couple of years ago when he arrived at the University of Southern California (USC) and became Principal Investigator of the USC Stem Cell.
Chen started the study from the assumption that hair follicle injury has an effect on the neighboring environment. So the environment can generate new hairs to sprout and your hair regenerates.
To verify this idea the scientist conducted an experiment on mice. They tried pulling out hairs in various densities and patterns. When plucking out all the hairs the hair grew back but no extra hairs sprouted. When they tried plucking the hairs form a circular area of 6mm in diameter and with a low-density the hair did not regenerate. The best outcomes were obtained when the circular area had a higher density and its diameter was between 3 and 5 mm. After the plucking process the hair regenerated and new strands of hair grew. The number of hair strands started from 450 and reached up to 1.300.
What lies behind this pluck-to-thicken method is the “quorum sensing” principle. This mechanism observes how a system reacts to targeted stimuli which affect only some of the members. This implies that the removal of some hairs will generate nearby hair follicles to react by growing hair. According to the researchers the inflammation under the skin adapts to the intensity of the damage which the hair suffers.
A molecular analysis proved that the follicles send distress signals to the neighbors. This releases inflammatory proteins which makes the immune cells gather at the “scene of the crime”. The immune cells produce molecules which, when in large numbers, send signals to both plucked and un-plucked follicles to sprout hair.
Chen noted that this study is a good example of how a basic research can open the path to a work with probable translational value. He also added:
“The implication of the work is that parallel processes may also exist in the physiological or pathogenic processes of other organs, although they are not as easily observed as hair regeneration.”
Image Source: Hair transplat UK
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