Growth hormone (GH) treatment is usually used during childhood but a new study has exposed a serious health condition that may be fatal in nature.
According to the researchers, they have found strong evidences suggesting strong link between hormones for growth and hemorrhagic stroke.
The research was conducted by Amélie Poidvin and colleagues from University Paris Diderot.
For the study, the researchers involved 6,874 children with idiopathic isolated GH deficiency or short stature who started GH treatment between 1985 and 1996. The researchers evaluated the participants’ adult morbidity data between 2008 and 2010. These medical records were used to validate cerebrovascular events in these participants.
The standard definitions of intracerebral hemorrhage, subarachnoid hemorrhage and ischemic stroke were taken into account to classify imaging data.
The researchers further compared these data with those of population incidence of stroke, collected from registries between 2000 and 2012.
There was a significant higher stroke risk among participants treated with GH in childhood than the registry references.
“Patients treated with GH worldwide should be advised about this association and further studies should evaluate the potentially causal role of GH treatment in these findings,” the authors wrote in the research paper.
The study was published online in Neurology on Thursday.